Tuning the twisting in helical nanowires | A metal alloy that is stronger when cold | Bringing up baby | Dipeptide repeat peptides on the attack | Connecting DNA damage to fibrosis | Coffee, tea, and chocolate converge | Old and older, cold and colder | Genome editing corrects a muscle disease | Caught in the act of making protein | Surprise found by γ-ray metal detector | The earthquake that rocked northern Chile | Optically manipulating superconductors | Cofactors linked to nutrient limitation | Watching nucleation pathways in calcite | Bringing in the agent of your own destruction | Liquid crystals on a deformable substrate | Protein markers of cyanobacterial stress

A long noncoding RNA helps cells divide | A drug's two-part way to block dopamine | Anthropogenic de-icing on a grand scale | Tolerating aluminum | Layers of ways to control drug release | Quantum imaging of Schrödinger's cat | An edgy way to transform carbon dioxide | When genetic diversity hurts the kids

A serum protein that tags along when pathogens enter cells triggers an immune reaction to them. Authors: Jerry C. H. Tam, Susanna R. Bidgood, William A. McEwan, Leo C. James

Dynamical shape-changing materials result from merging active liquid crystals with soft deformable vesicles. Authors: Felix C. Keber, Etienne Loiseau, Tim Sanchez, Stephen J. DeCamp, Luca Giomi, Mark J. Bowick, M. Cristina Marchetti, Zvonimir Dogic, Andreas R. Bausch

Repeated structural motifs encoded by disease genes impair RNA metabolism and cause cell death. [Also see Perspective by West and Gitler] Authors: Ilmin Kwon, Siheng Xiang, Masato Kato, Leeju Wu, Pano Theodoropoulos, Tao Wang, Jiwoong Kim, Jonghyun Yun, Yang Xie, Steven L. McKnight

Terahertz pump-probe spectroscopy reveals the oscillations of a superconducting order parameter at twice the pump frequency. [Also see Perspective by Pashkin and Leitenstorfer] Authors: Ryusuke Matsunaga, Naoto Tsuji, Hiroyuki Fujita, Arata Sugioka, Kazumasa Makise, Yoshinori Uzawa, Hirotaka Terai, Zhen Wang, Hideo Aoki, Ryo Shimano

The presence of a magnetic field helps control the balance among different assembly forces. Authors: Gurvinder Singh, Henry Chan, Artem Baskin, Elijah Gelman, Nikita Repnin, Petr Král, Rafal Klajn

A high-entropy alloy shows exceptional mechanical properties under cryogenic conditions. Authors: Bernd Gludovatz, Anton Hohenwarter, Dhiraj Catoor, Edwin H. Chang, Easo P. George, Robert O. Ritchie

Calcium carbonate crystal nucleation occurs via direct formation from solution and transformation from less stable phases. Authors: Michael H. Nielsen, Shaul Aloni, James J. De Yoreo

Early exposure of material produced in a supernova suggests an asymmetric explosion from the white dwarf progenitor. Authors: Roland Diehl, Thomas Siegert, Wolfgang Hillebrandt, Sergei A. Grebenev, Jochen Greiner, Martin Krause, Markus Kromer, Keiichi Maeda, Friedrich Röpke, Stefan Taubenberger

The intense and anomalous seismicity preceding the mainshock was the final step of a slow slip event. Authors: S. Ruiz, M. Metois, A. Fuenzalida, J. Ruiz, F. Leyton, R. Grandin, C. Vigny, R. Madariaga, J. Campos

An intricate triangular complex containing two iron atoms makes up the active site cofactor of a bacterial alkaline phosphatase. [Also see Perspective by Moore] Authors: Shee Chien Yong, Pietro Roversi, James Lillington, Fernanda Rodriguez, Martin Krehenbrink, Oliver B. Zeldin, Elspeth F. Garman, Susan M. Lea, Ben C. Berks

The composition of cyanobacterial proteins reflects nutrient stress in central Pacific Ocean ecosystems. [Also see Perspective by Moore] Authors: Mak A. Saito, Matthew R. McIlvin, Dawn M. Moran, Tyler J. Goepfert, Giacomo R. DiTullio, Anton F. Post, Carl H. Lamborg

Multiple proxies from ice cores show the spatial pattern of warming in Greenland over the last deglaciation. Authors: Christo Buizert, Vasileios Gkinis, Jeffrey P. Severinghaus, Feng He, Benoit S. Lecavalier, Philippe Kindler, Markus Leuenberger, Anders E. Carlson, Bo Vinther, Valérie Masson-Delmotte, James W. C. White, Zhengyu Liu, Bette Otto-Bliesner, Edward J. Brook

The genetic origins of coffee’s constituents reveal intriguing links to cacao and tea. Authors: France Denoeud, Lorenzo Carretero-Paulet, Alexis Dereeper, Gaëtan Droc, Romain Guyot, Marco Pietrella, Chunfang Zheng, Adriana Alberti, François Anthony, Giuseppe Aprea, Jean-Marc Aury, Pascal Bento, Maria Bernard, Stéphanie Bocs, Claudine Campa, Alberto Cenci, Marie-Christine Combes, Dominique Crouzillat, Corinne Da Silva, Loretta Daddiego, Fabien De Bellis, Stéphane Dussert, Olivier Garsmeur, Thomas Gayraud, Valentin Guignon, Katharina Jahn, Véronique Jamilloux, Thierry Joët, Karine Labadie, Tianying Lan, Julie Leclercq, Maud Lepelley, Thierry Leroy, Lei-Ting Li, Pablo Librado, Loredana Lopez, Adriana Muñoz, Benjamin Noel, Alberto Pallavicini, Gaetano Perrotta, Valérie Poncet, David Pot, Priyono, Michel Rigoreau, Mathieu Rouard, Julio Rozas, Christine Tranchant-Dubreuil, Robert VanBuren, Qiong Zhang, Alan C. Andrade, Xavier Argout, Benoît Bertrand, Alexandre de Kochko, Giorgio Graziosi, Robert J Henry, Jayarama, Ray Ming, Chifumi Nagai, Steve Rounsley, David Sankoff, Giovanni Giuliano, Victor A. Albert, Patrick Wincker, Philippe Lashermes

A mutation that causes muscular dystrophy in mice can be corrected by genome editing, which prevents the disease from developing. Authors: Chengzu Long, John R. McAnally, John M. Shelton, Alex A. Mireault, Rhonda Bassel-Duby, Eric N. Olson

The structure of an intermediate shows how the ribosome moves transfer RNAs from one binding site to another. Authors: Jie Zhou, Laura Lancaster, John Paul Donohue, Harry F. Noller

In flies, arginine-rich proteins and RNA repeats contribute to a common genetic cause of neuronal cell death. [Also see Perspective by West and Gitler] Authors: Sarah Mizielinska, Sebastian Grönke, Teresa Niccoli, Charlotte E. Ridler, Emma L. Clayton, Anny Devoy, Thomas Moens, Frances E. Norona, Ione O. C. Woollacott, Julian Pietrzyk, Karen Cleverley, Andrew J. Nicoll, Stuart Pickering-Brown, Jacqueline Dols, Melissa Cabecinha, Oliver Hendrich, Pietro Fratta, Elizabeth M. C. Fisher, Linda Partridge, Adrian M. Isaacs

A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.

Australians are constantly told that our economy is ‘“in transition.”’ We need to move up the global value chain, build knowledge-based industries, prepare for the Asian Century, and be the “food bowl of the world.” These are grand ambitions that we share with many other nations, in our region and beyond. The question for all of us is: How? Author: Ian Chubb

Residues on pottery suggest close ties between Mesoamerica and cultures to the north. Author: Michael Bawaya

A massive explosion in a nearby galaxy both confirms and confounds astronomers' expectations. Author: Daniel Clery

Researchers are scouring the now-barren Arabian Peninsula to uncover its hidden role in ancient human migration. Author: Andrew Lawler

Nuclear magnetic resonance spectroscopy of a glass under pressure adds to our understanding of network structure [Also see Report by Edwards et al.] Author: Randall E. Youngman

Domestication of rabbits led to changes across the genome, particularly in regions related to brain development [Also see Report by Carneiro et al.] Author: Kirk E. Lohmueller

Radio-wave interferometry provides an accurate measurement of cosmic distances [Also see Report by Melis et al.] Author: Léo Girardi

Cells use a piston-driven mechanism, among others, to migrate [Also see Report by Petrie et al.] Authors: Douglas W. DeSimone, A. Rick Horwitz

Genetic data elucidate the population history of the North American Arctic [Also see Research Article by Raghavan et al.] Author: Robert W. Park

What does the “Mississippi baby” tell us about curing HIV-1 infection? Authors: Janet D. Siliciano, Robert F. Siliciano

Brucker and Bordenstein (Reports, 9 August 2013, p. 667) claim that adaptive codivergence of gut bacteria with hosts contributes to hybrid lethality. Yet, they provide no evidence for coadaptation of bacteria and Nasonia hosts. Their data on hybrid viability suggest that bacteria contribute to inviability only because intrinsic hybrid dysfunction increases susceptibility to free-living bacteria. Hologenomic speciation remains testable speculation without experimental support. Authors: James Angus Chandler, Michael Turelli